Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death.
It has been used orally in dogs, cats and some wildlife species for over 10 years. After ingestion, it begins killing adult fleas within 30 minutes, and effects continue for up to 48 hours. Nitenpyram is safe to use on puppies and kittens as young as four weeks old if they weigh at least 2 pounds (0.91Â kg). Panting and excitement, as well as other symptoms, have been noted in cats and dogs within 2 hours of administration. In heavily infested animals, it can cause extreme itching as the fleas die. There is no known antidote for nitenpyram poisoning.
Though nitenpyram is used to kill adult fleas quickly on an infested animal, it does not kill insect eggs and has no long-term activity. Thus, it is not effective as a long-term flea preventative; however, it can be repeatedly applied over the course of several days to eradicate a single instance of infestation. Nitenpyram can be combined with a longer-term flea preventative like fipronil or lufenuron to prevent reinfestation.
References
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External links
- Nitenpyram in the Pesticide Properties DataBase (PPDB)
- Freedom of Information summary (NADA 141-053), US Food and Drug Administration
